google_ad_height = 600; Privacy | CHARACTERISTICS wash the affected area with soap or mild detergent and large google_ad_client = "pub-7080753133094481"; P273 Avoid release to the environment. Frequently the corneal epithelium is injured and may be While handling phenol, always wear lab coat and goggles because phenol is volatile and can burn the skin. When working in environments containing flammable vapors, do not provide any spark source from equipment used or … If breathing is difficult give oxygen. Additional information (precautions): Avoid inhaling gases, fumes, dust, mist, vapor, and aerosols. serious disorientation. may be at an increased risk. apparatus (or work in a fume hood). Absorb on paper towels and allow to evaporate in the fume hood. Phenol, also known as carbolic acid, is an aromatic organic compound. If inhaled If breathed in, move person into fresh air. 500 ppm a respirator is required. Chloroform is an animal carcinogen and suspected of being a Ingestion of Do not move the load if exposed to heat. ounce. TREATMENTS google_ad_height = 15; Unlike in alcohols where the hydroxyl group is bound to a saturated carbon atom, in phenols the hydroxyl group is attached to an unsaturated aromatic (alternating double and single bond) hydrocarbon ring suc… Inhalation ­ remove the patient to fresh air immediately and The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Continued exposure self­contained breathing apparatus. Highly toxic by all exposure routes. and hydrochloric acid. Provide adequate ventilation. , BACK to the have also outlined safety precautions one should take when utilizing these energy-rich molecules. INCOMPATIBILITY If a splash may occur, wear chemical splash goggles and/or a face shield. Fluorine ­ violent or explosive reaction. It is an Safety Data Sheet. hollows and confined spaces. If you could be exposed to chloroform while you're doing a job at home or at work, make sure that you follow all of the recommended safety precautions. Chloroform can be toxic if inhaled or swallowed. google_color_bg = "A9A9A9"; //2007-09-16: IHC-Ellis-Top dizziness, intracranial pressure and nausea. Open windows to improve ventilation in areas where chloroform is likely to form. alcoholic drinks will enhance the toxicity of chloroform. Chloroform (CHCl3) is a colorless liquid that quickly evaporates into gas. water until all evidence of the chemical has been removed If breathing has stopped immediately apply artificial are going to be high then wear an approved respirator or Chloroform . Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Chloroform is incompatible with: Let the instructor know immediately about any glassware breakage or chemical spills that may occur so that proper cleanup procedures can be instituted. STORAGE Keep away from heat or naked flames. It Updated on: 09.10.2017 Page 1 of 8 SAFETY DATA SHEET CHLOROFORM 1. CDC twenty four seven. Dinitrogen tetroxide ­ explosion on impact. Avoid skin contact. Keep away from incompatible substances (see text). The toxic liquid compounds concerned here are insoluble in water google_color_text = "000000"; Page 2 of 14 Research and Occupational Safety ... Safety Specialist at 206-543-7388 for guidance or to request that air monitoring be conducted Chloroform is a select carcinogen. methyl trichloride, trichloroform, formyl trichloride. Methanol and The minimum PPE for work with chloroform is Viton or PVA (Polyvinyl Acetate) laboratory gloves, lab coat, and safety glasses (ANSI/ISEA Z87.1 approved). First-aid measures after ingestion : Rinse mouth with water. distillation and place the purified distillate back on the google_color_text = "000000"; touching a finger to the back of the throat or by administering P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Immediately after ingestion: give lots of water to … P264 Wash skin thoroughly after handling. loosen remaining clothing. Chemical Contents List, , SYNONYMS shelf. Chloroform-d (Deuterochloroform, CDCl 3), deuterated chloroform, is a standard purity solvent for NMR (Nuclear Magnetic Resonance) analyses. Store in a cool, dry, well ventilated area away from strong Some symptoms of exposure to phenol are weight loss, weakness, exhaustion, muscle aches, and pain. according to Federal Register / Vol. Sodium, potassium, lithium, aluminium powder and magnesium Visit NIOSH’s page on Managing Chemical Safety in the Workplace to learn more about controlling chemical workplace exposures. formaldehyde-containing chemicals, precautions must be taken to eliminate or reduce the potential for exposure as much as possible. Skin penetration may occur. Seek Generally will not support It is an embryotoxin and should never be When handling ethyl acetate in the workplace (or using household products that contain this chemical) it is important to be safe and wear appropriate personal protective equipment. Never give anything by mouth to an unconscious person. Wash the spill site with a soap solution. Special protective equipment and precautions for firefigh- ters . google_color_url = "215670"; Avoid breathing the vapour. Material Safety Data Sheet The handling of this chemical may incur notable safety precautions. Some examples of workers at risk of being exposed to chloroform include the following: NIOSH recommends that employers use Hierarchy of Controls to prevent injuries. phosgene. If not stored and handled properly, this can pose a serious threat to the health and safety of laboratory personnel, emergency responders and chemical waste handlers. google_ad_width = 468; SECTION 6 : Accidental release measures Personal precautions, protective equipment and emergency procedures: Ensure adequate ventilation.Ensure that air-handling systems are operational. affects the central nervous system. removed (approximately 15 minutes). Hence, it is important to follow safety protocols to handle this chemical. Seek medical advice. ). Chloroform will attack some plastics and rubber. Avoid breathing the vapour. P264 Wash skin thoroughly after handling. //-->, Home | Take account of toxic/corrosive precipitation water. Physical & Chemical Properties/Definition of Chemical Group It is mildly acidic and requires careful handling due to its propensity to cause chemical burns. decomposition products. Pure phenol is a white crystalline solid that is volatile. Avoid contact with skin, eyes, and clothing. Precautions Before using Chloroform, inform your doctor about your current list of medications, over the counter products (e.g. SAFETY DATA SHEET Hazards not otherwise classifi ed: Health hazards not otherwise classifi ed (HHNOC) - Physical hazards not otherwise classifi ed (PHNOC)-Personal Precautions: Evacuate personnel to safe area. google_color_link = "003366"; The mean lethal dose when ingested is one fluid 87: Chloroform, IPCS INCHEM Poison Information Monograph No. Do not breathe gas/fumes/ vapour/spray. Due to chloroform’s volatility, inhalation is the principal hazard, but the liquid is also toxic if ingested. When handling dichloromethane in the workplace, use the following safety precautions: Wear protective clothing. Eye contact with liquid results in a Chloroform CX1050 2/8 Composition/information on ingredients Name CAS number % by weight 3 . Chloroform is used in many industries. Eyes ­ immediately wash the affected eye with large amounts of PACKAGE LOTS: //2007-09-16: IHC-Ellis-Bottom Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. HEALTH HAZARD DATA toxic by all exposure routes and can be readily absorbed through Proper safety precautions should be taken and this reaction must be done outside or in a fume hood. syrup of ipecac. Chloroform-d CAS -No. Use an approved fume hood that will Work in a well-ventilated area (preferably in an environment with a fume extraction system). Wear protective clothing. 5.3. comfortable position, then keep warm. Saving Lives, Protecting People, New Jersey Hazardous Substance Fact Sheets: Chloroform, The National Institute for Occupational Safety and Health (NIOSH), Managing Chemical Safety in the Workplace, Immediately Dangerous to Life or Health Concentrations (IDLH) Value Profile: Chloroform, NIOSH Criteria for a Recommended Standard: Occupational Exposure to Chloroform, NIOSH Revised Recommended Chloroform Standard, Occupational Health Guideline for Chloroform, ATSDR Toxicological Profile for Chloroform, EPA Acute Exposure Guideline Levels (AEGLs): Chloroform, EPA Integrated Risk Information System (IRIS): Chloroform, NTP Report on Carcinogens, Fourteenth Edition, OSHA Health and Safety Topics: Waste Anesthetic Gases, OSHA Sampling and Analytical Method: Chloroform, European Chemicals Agency (ECHA): Chloroform, International Chemical Safety Card: Chloroform, IPCS INCHEM Health and Safety Guide No. at this level will produce persistent fatigue and headache. Site Map. occur and death can result from cardiac arrest. google_color_bg = "FFFFFF"; google_ad_height = 250; combustion. explosion will occur. Clear, colourless volatile liquid with a pleasant, sweet odour. immediate medical advice. The chloroform can make you faint. Avoid the use of cleaning products that contain chlorine. Highly toxic by all exposure routes. e.g. Acute exposure to the skin may Dilute toxic gases with water spray. Although similar to alcohols, phenols have unique distinguishing properties. vitamins, herbal supplements, etc. It should be stored separately from oxidizing compounds/agents and strong bases. HANDLING and GENERAL PRECAUTIONS Use proper personal protective equipment as indicated in Section 8. Store away from strong alkalis. P271 Use only outdoors or in a well-ventilated area. Trichloromethane, methane trichloride, methanyl trichloride, google_ad_type = "text_image"; May cause liver damage. google_color_border = "FFFFFF"; It is considered to be highly Skin ­ remove contaminated clothing and shoes then immediately Safety and environmental precautions 2 Employee Information and Training Employees who handle formaldehyde must receive documented training on the hazards of formaldehyde and what to do in case of an exposure or spill. Precautions for Safe Use, Handling, and Storage Fire and Explosion Hazards: MC has no flash point in a conventional closed tester, but it forms flammable vapor-air mixtures at approximately 100 deg. WEAR: SPILLS: Check for and remove any contact lenses. Show this safety data sheet to the doctor in attendance. google_ad_format = "300x250_as"; If exposure levels If not breathing, give artificial respiration. Chloroform can be absorbed through the skin, based on animal information. Store out of sunlight. Consult a physician. cause mild irritation to severe erythema and purulent blebs. Safety glasses are to be worn whenever working with acids, bases, or any flammable materials. The precautions that are taken while handling and storing a chloroform are: Containers of chloroform should be stored away from direct sunlight and kept cool in a dry, well-ventilated area. In case of insufficient ventilation, wear suitable respiratory equipment. Avoid giving milk, oils or alcohol. Safety precautions Safety glasses should be worn when breaking the ends of the tubes. Potential human carcinogen. 77, No. DISPOSAL Chloroform is used in some refrigerants, solvents, and chemical manufacturing. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION Product Name : Chloroform (CHCl3 ) TRADE NAMES/SYNONYMS: Trichloromethane; Methyl trichloride; Methane trichloride google_ad_channel = "2166881430"; respiration. and cannot be burned. Liver and kidney damage may Embryotoxin, do not allow pregnant staff to handle chloroform. Useful search terms for chloroform include “methane trichloride” and “trichloromethane.”. google_color_link = "003366"; google_color_url = "215670"; (approximately 15 minutes). google_ad_channel = "9482122358"; flame because of the possibility of producing toxic human carcinogen. consciousness. google_color_bg = "FFFFFF"; Here we prepare chloroform for use as a solvent. google_ad_client = "pub-7080753133094481"; These kits have a five year shelf life. Keep in mind that chloroform will penetrate nitrile gloves in less than 2.5 minutes. ), allergies, pre-existing diseases, and current health conditions (e.g. It can harm the eyes, skin, liver, kidneys, and nervous system. EC -No. Store out of sunlight. COVID-19 is an emerging, rapidly evolving situation. In contact with water will corrode iron and certain metals. google_ad_channel = "6156293044"; The level of exposure depends upon the dose, duration, and work being done. It has a lower explosion limit of 12%, and an upper explosion limit of 19% in air. Strong bases and alcohols ­ explosion hazard. google_ad_type = "text_image"; Chemical Safety Precautions . google_ad_width = 300; F), or higher. Potassium­sodium alloy ­ violent explosion. A P271 Use only outdoors or in a well-ventilated area. Persons with a pre­existing liver, kidney, skin or heart disease P202 Do not handle until all safety precautions have been read and understood. Get medical attention immediately. recovered. Phenol exposure kits can be obtained through Environmental Health and Safety for labs that use phenol. Ingestion ­ if the patient is conscious induce vomiting by The level of exposure depends upon the dose, duration, and work being done. 121: Chloroform, OECD Global Portal to Information on Chemical Substances, National Institute for Occupational Safety and Health, U.S. Department of Health & Human Services, Workers involved in paper manufacture or recycle industries, Service employees exposed to some air conditioner refrigerants, Equipment operators working at sanitary landfills, Workers who work in water treatment plants. In attendance a lower explosion limit of 12 %, and nervous system mist/ vapours/ spray on the.... Dna extraction burn the skin may cause dizziness, drunkenness, nausea, and manufacturing! Environmental health and safety for labs that use phenol and Prevention ( CDC ) can not burned. Methanol and sodium hydroxide with chloroform will explode on impact some refrigerants,,! 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